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近日,解放军总医院肿瘤医学部生物治疗科主任韩为东/聂晶团队与军事医学研究院伯晓晨/陈河兵团队在《JournalofClinicalInvestigation》期刊(影响因子19.456)合作发表论文,阐明DNA去甲基化药物地西他滨增强PD-1抑制剂抗瘤效能的分子与细胞学机制。
Molecular and serological investigation of 2019-nCoV infected patients: implication of multiple shedding routes
2019-nCoV Wuhan pneumonia epidemiology swabs intestine
2020/6/12
In December 2019, a novel coronavirus (2019-nCoV) caused an outbreak in Wuhan, China, and soon spread to other parts of the world. It was believed that 2019-nCoV was transmitted through respiratory tr...
Plantar Pressures During Long Distance Running:An Investigation of 10 Marathon Runners
Marathon running in-shoe pressure insoles plantar pressure foot dominance
2016/7/7
The objective of this study was to record plantar pressures using an in-shoe measuring system before, during, and after a marathon run in ten experienced long-distance runners with a mean age of 37.7 ...
Prediagnostic selenium status and hepatobiliary cancer risk in the European Prospective Investigation into Cancer and Nutrition cohort
hepatocellular carcinoma selenium selenoprotein P prospective cohort liver cancer hepatobiliary cancer selenium status
2018/12/13
Background: Selenium status is suboptimal in many Europeans and may be a risk factor for the development of various cancers, including those of the liver and biliary tract.
Do eating habits differ according to alcohol consumption? Results of a study of the French cohort of the European Prospective Investigation into Cancer and Nutrition (E3N-EPIC)
cohort study nutrients energy E3N-EPIC
2016/6/14
The potential of dietary habits to confound the association
between alcohol consumption and health needs further study.
Use of biological markers to validate self-reported dietary intake in a random sample of the European Prospective Investigation into Cancer United Kingdom Norfolk cohort
Validity biomarkers urinary nitrogen
2016/6/14
The validity of dietary assessment methods should
be established before diet-disease associations are reported.
A tracer investigation of obligatory oxidative amino acid losses in healthy, young adults
cyst(e)ine leucine humans
2016/6/1
Estimation of the minimum requirement for indispensable
amino acids (IAAs) has been attempted by assuming
that obligatory oxidative losses (OOLs) of IAAs can be approximated
from nitrogen losses an...
Validation of a self-administered food-frequency questionnaire administered in the European Prospective Investigation into Cancer and Nutrition (EPIC) Study: comparison of energy, protein, and macronutrient intakes estimated with the doubly labeled water, urinary nitrogen, and repeated 24-h dietary recall methods
Validity biomarkers energy expenditure
2016/6/1
The validation of dietary assessment instruments is
critical in the evaluation of diet as a chronic disease risk factor.
The association between dietary saturated fatty acids and ischemic heart disease depends on the type and source of fatty acid in the European Prospective Investigation into Cancer and Nutrition–Netherlands cohort,
saturated fatty acids ischemic heart disease nutrition epidemiology follow-up studies
2018/11/27
Background: The association between saturated fatty acid (SFA) intake and ischemic heart disease (IHD) risk is debated.
Influence of a montmorency cherry juice blend on indices of exercise-induced stress and upper respiratory tract symptoms following marathon running—a pilot investigation
Recovery URTS Exercise-induced inflammation Muscle damage
2015/7/30
Prolonged exercise, such as marathon running, has been associated with an increase in respiratory mucosal inflammation. The aim of this pilot study was to examine the effects of Montmorency cherry jui...
Effects of short-term ingestion of Russian Tarragon prior to creatine monohydrate supplementation on whole body and muscle creatine retention and anaerobic sprint capacity:a preliminary investigation
Creatine supplementation Russian Tarragon Anaerobic capacity Muscle creatine
2015/7/29
Extracts of Russian Tarragon (RT) have been reported to produce anti-hyperglycemic effects and influence plasma creatine (Cr) levels while supplementing with creatine monohydrate (CrM). The purpose of...
An Investigation of the Asymptomatic Limb in Unilateral Lateral Epicondylalgia
TENNIS ELBOW BILATERAL MOTOR SYSTEM ULTRASOUND IMAGING
2017/4/20
Introduction: Musculoskeletal ultrasound (MSUS) imaging is used to investigate features of tendinosis. Recent studies have reported tendon pathology not only in the symptomatic tendon but also in the ...
Investigation and management of paraneoplastic neurological syndromes
Investigation management paraneoplastic neurological syndromes
2015/3/17
Paraneoplastic neurological syndromes (PNS) are rare, but severely debilitating complications of cancer. These disorders are a non-metastatic phenomenon and are considered to have an immune-mediated a...
Investigation of peptide nucleic acid fluorescence in situ hybridization for diagnosis of ventilator-associated pneumonia in bronchoalveolar lavage specimens
QuickFISH PNA FISH VAP BAL ventilator-associated pneumonia bronchoalveolar lavage AdvanDx diagnosis
2015/1/28
Investigation of peptide nucleic acid fluorescence in situ hybridization for diagnosis of ventilator-associated pneumonia in bronchoalveolar lavage specimens.
Investigation of peptide nucleic acid fluorescence in situ hybridization for diagnosis of ventilator-associated pneumonia in bronchoalveolar lavage specimens
QuickFISH PNA FISH VAP BAL ventilator-associated pneumonia bronchoalveolar lavage AdvanDx diagnosis
2015/1/19
Investigation of peptide nucleic acid fluorescence in situ hybridization for diagnosis of ventilator-associated pneumonia in bronchoalveolar lavage specimens.