搜索结果: 1-15 共查到“知识库 histone”相关记录20条 . 查询时间(0.011 秒)
Nitric oxide coordinates growth, development, and stress response via histone modification and gene expression
nitric oxide stress response gene expression plant physiology plant ability
2023/12/1
Nitric oxide (NO) is a signaling molecule with multiple regulatory functions in plant physiology and stress response. In addition to direct effects on transcriptional machinery, NO executes its signal...
Identification of Histone Deacetylase 2 as a Functional Gene for Skeletal Muscle Development in Chickens
Histone Deacetylas Post Genome-Wide Association Study Gene Expression Myogenesis
2016/5/19
A previous genome-wide association study (GWAS) exposed histone deacetylase 2 (HDAC2) as a possible candidate gene for breast muscle weight in chickens. The present research has examined the possible ...
Interaction between cellular retinoic acid-binding protein II and histone hypoacetylation in renal cell carcinoma
Retinoic acid Cellular retinoic acid-binding proteins Histone deacetylase Renal cell carcinoma
2015/7/28
Renal cell carcinoma is a rare but serious malignancy. Since a reduction in the level of retinoic acid receptor beta 2 (RARbeta2) expression in cancer cells due in part to histone hypoacetylation whic...
SETD1 HISTONE 3 LYSINE 4 METHYLTRANSFERASE COMPLEX COMPONENTS IN EPIGENETIC REGULATION
EPIGENETICS H3K4 METHYLTRANSFERASE
2015/5/25
Setd1 histone 3 lysine 4 methyltransferases are critical for epigenetic regulation and gene expression. Setd1a is multiprotein complex comprised of several critical subunits including wdr82, which is ...
Analysis of Histone Lysine Methylation Using Mass Spectrometry
MudPIT histones transcription
2015/5/25
Histones are highly basic proteins which when digested by trypsin are hard to analyze using mass spectrometry. Because histones are basic nuclear proteins, a nuclei prep followed by acid extraction is...
Structural and functional characterization of the unique N-terminus of Cse4p, A histone H3 -like protein at the S. cerevisiae centromere
Budding yeast the yeast protein protein fission yeast etc
2014/12/11
The budding yeast (S. cerevisiae) centromere component, Cse4p is an evolutionarily conserved histone H3-like protein, with homologues identified in fission yeast, worm, fly and human. All histone H3-l...
The building of a centromeric nucleosome: Biochemical analysis and comparison of Cse4p, histone H3 and Cse4-286p to define the unique assembly pathway of a Cse4p nucleosome
Nucleosome chromatin structure octamer core protein chromatin structure cell nuclear cells the cellular mechanisms
2014/12/11
Nucleosomes are the most fundamental unit of chromatin structure, which is composed of ~～145 bp of DNA wrapped around an octamer of core histones H2A, H2B, H3 and H4. Chromatin structure plays a role ...
Effects of Histone Deacetylase Inhibitors on Vitamin D Activity in Human Breast Cancer Cells
Sulforaphane histone deacetylase inhibitors vitamin D receptor
2014/11/7
Breast cancer is one of the leading causes of death in women cancer cases worldwide. Cancer is the result of environmental and genetic factors that contribute to alterations in cellular control, proli...
HISTONE DEACETYLASE INHIBITORS TRICHOSTATIN A (TSA) AND SULFORAPHANE (SFN) MODULATE VITAMIN D RESPONSIVE CYP24 GENE EXPRESSION in 3T3-L1 PREADIPOCYTES
TRICHOSTATIN A (TSA) SULFORAPHANE (SFN), CYP24 3T3-L1 PREADIPOCYTES
2014/11/7
Vitamin D plays an important role in preserving healthy bones, and has additional roles in the body, including modulation of cell growth, differentiation, neuromuscular and immune function, and anti-i...
Potential role of histone deacetylases in the development of the chick and murine retina
Development Epigenetics Retina HDACs
2015/5/22
The epigenetic state of any cell is, in part, regulated by the interaction of DNA with nuclear histones. Histone tails can be modified in a number of ways that impact on the availability of DNA to int...
Sliding and peeling of histone during chromatin remodelling
Sliding peeling of histone chromatin remodelling Subcellular Processes
2011/8/3
Abstract: ATP-dependent chromatin remodeling enzymes (CRE) are bio-molecular motors in eukaryotic cells. These are driven by a chemical fuel, namely, adenosine triphosphate (ATP). CREs actively partic...
Mapping Dynamic Histone Acetylation Patterns to Gene Expression in Nanog-depleted Murine Embryonic Stem Cells
Mapping Dynamic Histone Acetylation Patterns Gene Expression in Nanog-depleted Murine Embryonic Stem Cells
2010/11/15
Embryonic stem cells (ESC) have the potential to self-renew indefinitely and to differentiate into any of the three germ layers. The molecular mechanisms for self-renewal, maintenance of pluripotency ...
The role of histone acetylation in sexual differentiation of the mouse brain
Biological sciences Histone acetylation Sexual differentiation Valproic acid
2014/11/4
Sex differences are widespread throughout the nervous system and have been identified in relation to almost every neural characteristic, from basic anatomy, to behavior, to differences in the prevalen...
Are Lymphoblastoid Cell Lines Suitable to Study Increased SMN Gene Expression by Histone Deacetylase Inhibitors?
Spinal muscular atrophy survival motor neuron gene histone deacetylase inhibitors treatment
2009/6/16
Aim: In this preliminary study, we aimed to analyze the effect of sodium butyrate (NB) and phenylbutyrate (PB), belonging to the class of histone deacetylase (HDAC) inhibitors, on lymphoblastoid cell ...
Sperm Nuclear Histone to Protamine Ratio in Fertile and Infertile Men：Evidence of Heterogeneous Subpopulations of Spermatozoa in the Ejaculate
Sperm DNA male infertility
2008/12/24
Sperm protamine deficiency is observed in a subset of infertile men, suggesting that the relative histone to protamine ratio may be altered in the spermatozoa of these men. We measured the ratio of ...