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Five Rice Seed-Specific NF-YC Genes Redundantly Regulate Grain Quality and Seed Germination via Interfering Gibberellin Pathway
NF-YCs 种子发育 赤霉素 籽粒品质
2023/3/9
NF-YCs are important transcription factors with diverse functions in the plant kingdoms including seed development. NF-YC8, 9, 10, 11 and 12 are close homologs with similar seed-specific expression pa...
High-resolution temporal dynamic transcriptome landscape reveals a GhCAL-mediated flowering regulatory pathway in cotton (Gossypium hirsutum L.)
棉花开花 相关基因 GhCAL
2024/5/17
本研究利用不同熟性的棉花高分辨率时间动态转录组，鉴定到棉花开花相关基因GhCAL，并对其介导的棉花开花调节途径进行了解析。研究发现GhCAL基因沉默的转基因棉花植株花芽分化和开花时间显著延迟，GhCAL能够与GhAP1-A04/GhAGL6-D09形成异源二聚体，同时调节GhAP1-A04和GhAGL6-D09的表达。GhAP1-A04和GhAGL6-D09沉默的棉花植株也表现出明显的开花延迟。因...
NAC transcription factor ONAC066 positively regulates disease resistance by suppressing the ABA signaling pathway in rice
NACs ABA ONAC066 SA JA
2023/4/21
NAC transcription factors have been validated as important regulators in stress responses, but their molecular mechanisms in plant disease resistance are still largely unknown. Here we report that the...
Eggs early in complementary feeding increase choline pathway biomarkers and DHA: a randomized controlled trial in Ecuador
egg nutrition children choline betaine vitamin B-12 docosahexaenoic acid
2018/11/21
Background: Choline status has been associated with stunting among young children. Findings from this study showed that an egg intervention improved linear growth by a length-for-age z score of 0.63.
Odd-chain fatty acids as a biomarker for dietary fiber intake: a novel pathway for endogenous production from propionate
soluble fiber fermentation pentadecanoic heptadecanoic liver long-chain fatty acid
2018/11/14
Background: The risk of type 2 diabetes is inversely correlated with plasma concentrations of odd-chain fatty acids [OCFAs; pentadecanoic acid (15:0) and heptadecanoic acid (17:0)], which are consider...
Correlations of genes expression in PPAR signalling pathway with porcine meat quality traits
genetic markers Real-time PCR IMF Longissimus dorsi muscle pig
2016/8/1
The correlation of expression pattern of candidate genes in PPAR signalling pathway with meat quality traits in Longissimus dorsi muscle of pigs was investigated. Meat quality traits were measured and...
Anatomy and Dynamics of a Ligand-Binding Pathway in Myoglobin:The Roles of Residues 45,60,64 and 68
Humans Carbon Monoxide Myoglobin Recombinant Proteins Ligands Spectrum Analysis Protein Binding Kinetics Mutation Thermodynamics
2016/5/23
In order for diatomic ligands to enter and exit myoglobin, there must be substantial displacements of amino acid side chains from their positions in the static X-ray structure. One pathway, involving ...
The Effects of Glucagon-like Peptide-2 on the Tight Junction and Barrier Function in IPEC-J2 Cells through Phosphatidylinositol 3-kinase–Protein Kinase B–Mammalian Target of Rapamycin Signaling Pathway
Transepithelial Electrical Resistance Phosphatidylinositol 3-Kinase-Akt-mTOR Signaling Pathway
2016/5/20
Glucagon-like peptide-2 (GLP-2) is important for intestinal barrier function and regulation of tight junction (TJ) proteins, but the intracellular mechanisms of action remain undefined. The purpose of...
The motilin receptor agonist erythromycin stimulates hunger and food intake through a cholinergic pathway
hunger food intake motilin migrating motor complex erythromycin
2018/11/28
Background: Motilin-induced phase III contractions have been identified as a hunger signal. These phase III contractions occur as part of the migrating motor complex (MMC), a contractility pattern of ...
Transcription factor-pathway co-expression analysis reveals cooperation between SP1 and ESR1 on dysregulating cell cycle arrest in non-hyperdiploid multiple myeloma
coexpression cell cycle arrest multiple myeloma hyperdiploid
2016/1/25
Multiple myeloma is a hematological cancer of plasma B cells and remains incurable. Two major subtypes of myeloma, hyperdiploid MM (HMM) and non-hyperdiploid MM (NHMM), have distinct chromosomal alter...
Transcription factor-pathway co-expression analysis reveals cooperation between SP1 and ESR1 on dysregulating cell cycle arrest in non-hyperdiploid multiple myeloma
coexpression cell cycle arrest multiple myeloma hyperdiploid
2016/1/20
Multiple myeloma is a hematological cancer of plasma B cells and remains incurable. Two major subtypes of myeloma, hyperdiploid MM (HMM) and non-hyperdiploid MM (NHMM), have distinct chromosomal alter...
Melatonin protects against burn-induced hepatic oxidative injury by inducing HO-1 via the Nrf2 pathway
melatonin Nrf2 HO-1 4-HNE oxidative stress liver
2015/11/26
Melatonin exerts beneficial effects on early liver injury by modulating hepatic oxidative stress. In
order to understand the protective effect of melatonin against burn-induced hepatic injury we inv...
Effect of Patient-Focused Clinical Pathway on Anxiety, Depression and Satisfaction of Patients With Coronary Artery Disease: A Quasi-Experimental Study
Coronary Artery Disease Patient Satisfaction Anxiety Depression Clinical Pathways
2015/11/9
Background: Coronary artery diseases (CAD) are associated with psychological problems such as anxiety and depression in patients. Thus, management of these problems can consider as an important interv...
Ingestion of 10 grams of whey protein prior to a single bout of resistance exercise does not augment Akt/mTOR pathway signaling compared to carbohydrate
protein prior esistance exercise
2015/7/22
This study examined the effects of a whey protein supplement in conjunction with an acute bout of
lower body resistance exercise, in recreationally-active males, on serum insulin and insulin like gro...