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A Double-Blind Non-inferiority Clinical Study of Montelukast, a Cysteinyl Leukotriene Receptor 1 Antagonist, Compared with Pranlukast in Patients with Seasonal Allergic Rhinitis
comparative double blind study cysteinyl leukotriene receptor montelukast pranlukast seasonal allergic rhinitis
2010/11/17
Montelukast 5mg, 10mg once daily and the pranlukast 450mg/day showed significant improvements in the change from the baseline in the composite, daytime and nighttime nasal symptom scores, and the impr...
Therapeutic Effect of Montelukast, a Cysteinyl Leukotriene Receptor 1 Antagonist, on Japanese Patients with Seasonal Allergic Rhinitis
cysteinyl leukotriene receptor dose-response relationship montelukast rhinitis allergic seasonal
2010/11/17
Background: Secretion of nasal discharge was enhanced and airway-resistance in the nasal cavity was augmented, resulting in nasal congestion, when leukotrienes were administered to the nasal mucosa. T...
Clinical Evaluation of Leukotriene Receptor Antagonists in Preventing Common Cold-like Symptoms in Bronchial Asthma Patients
acute exacerbation asthma common cold-like symptoms ICS LTRAs
2010/11/18
Adult asthma patients undergoing treatment with LTRAs exhibit lower incidence rates of common cold-like symptoms than those not receiving LTRAs. LTRAs play an important role in reducing the incidence ...
Effect of Procaterol, a β2 Selective Adrenergic Receptor Agonist, on Airway Inflammation and Hyperresponsiveness
airway hyperresponsiveness allergic inflammation eosinophil murine model β2 adrenergic receptor agonist
2010/11/18
Background: β-agonists are frequently used as bronchodilators for asthma as not only a reliever but also a controller, and their utility has increased with the development of long-acting β2 selective ...
Tumor Necrosis Factor Receptor-associated Periodic Syndrome Mimicking Systemic Juvenile Idiopathic Arthritis
C-reactive protein (CRP) International League of Associations for Rheumatology (ILAR) criteria juvenile idiopathic arthritis (JIA) tumor necrosis factor receptor-associated periodic syndrome (TRAPS) tumor necrosis factor receptor super family 1A (TNFRSF1A)
2010/11/19
Background: We report two cases of tumor necrosis factor receptor-associated periodic syndrome (TRAPS) in patients in whom systemic juvenile idiopathic arthritis (JIA) had initially been diagnosed or ...
Population-based open-label clinical effectiveness assessment of the cysteinyl leukotriene receptor antagonist pranlukast
asthma pranlukast questionnaire symptom treatment
2010/11/26
Although the efficacy of cysteinyl leukotriene receptor antagonists in asthma therapy has been established through controlled clinical trials, there are no data concerning the effectiveness of their u...
Effect of a leukotriene receptor antagonist on the prevention of recurrent asthma attacks after an emergency room visit
β2-adrenergic receptor agonist asthma exacerbation leukotriene receptor antagonist montelukast
2010/11/24
In the montelukast group, the need for a rescue β-adrenergic receptor agonist was significantly decreased; 54.5% of patients in the montelukast group required use of β-adrenergic receptor agonist comp...
Clinical Use of β2-adrenergic Receptor Agonists Based on Their Intrinsic Efficacy
airway smooth muscle bronchial asthma desensitization Gs long-acting β2-agonists Rho β2-adrenergic receptors
2010/11/19
Clinical choice of β2-adrenergic receptor agonists (β2-agonists) is based on the parameter of receptor selectivity, potency, and duration of action. The guidelines for asthma management describe nothi...
Thyroid-Stimulating Hormone and Thyroid-Stimulating Hormone Receptor Structure-Function Relationships
Thyroid-Stimulating Hormone Thyroid-Stimulating Hormone Receptor Structure-Function Relationships
2014/3/31
Thyroid-stimulating hormone (TSH; thyrotropin) and TSH receptor (TSHR) are key proteins in the control of thyroid function. TSH synthesis in the anterior pituitary is stimulated by thyrotropin-releasi...