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Effect of modified immunotherapy with an allergen-pullulan conjugate in patients with Japanese cedar pollinosis
eosinophil immunotherapy Japanese cedar pollinossis mast cell seasonal allergic rhinitis Th1 cytokine Th2 cytokine
2010/11/25
Immunologic mechanisms of allergen immunotherapy are still incompletely understood. Immunotherapy of a higher maximum tolerance dose with reduced risks of systemic reactions, such as anaphylaxis, need...
Effect of a leukotriene receptor antagonist on cough receptor sensitivity and allergen-induced cough in a patient with atopic cough variant asthma
asthma atopy cough variant asthma leukotriene receptor antagonist
2010/11/29
A 24-year-old female patient with chronic dry cough, without wheezing and other symptoms, was diagnosed as atopic cough variant asthma (CVA) sensitized with house dust (HD) mite. To investigate the ef...
Effect of a thromboxane A2 receptor antagonist, ramatroban (BAY u 3405), on inflammatory cells, chemical mediators and non-specific nasal hyperreactivity after allergen challenge in patients with perennial allergic rhinitis
eosinophil nasal allergen challenge nasal mucosal reactivity perennial allergic rhinitis ramatroban thromboxane A2 receptor antagonist
2010/11/29
In some clinical studies performed in patients with perennial allergic rhinitis, ramatroban, a new thromboxane A2 receptor antagonist, significantly improved nasal symptoms. As yet the mechanism of ac...