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Cyclooxygenase Inhibition Limits Blood-Brain Barrier Disruption following Intracerebral Injection of Tumor Necrosis Factor-alpha in the Rat
cyclooxygenase-2 COX-2 COX-1 prostaglandin E2 neuroinflammation blood-brain barrier ischemia stroke matrix metalloproteinase MMP-3 MMP-9 gelatinase B stromelysin-1 oxidative stress indomethacin cyclooxygenase-1 glutathione free radicals MRI
2015/7/29
Increased permeability of the blood-brain barrier (BBB) is important in neurological disorders. Neuroinflammation is associated with increased BBB breakdown and brain injury. Tumor necrosis factor-alp...
中国医学科学院实验血液学国家重点实验室肖志坚课题组在Blood期刊发表文章"Unique features of primary myelofibrosis in Chinese.”
实验血液学 肖志坚课题组 Blood期刊 发表文章
2012/3/26
linical and laboratory features of 642 consecutive Chinese subjects with primary myelofibrosis (PMF) were analyzed and compared with those of 1054 predominately white subjects with PMF. Chinese subjec...
Peripheral blood Microchimerism in female renal recipients from male donors
Allograft function Microchimerism Renal transplantation
2009/12/24
The relation between microchimerism and allograft tolerance is still a mystery. In this study we determined the presence of peripheral blood microchimerism (PBMC) in female renal transplant recipients...
The risk of having a potentially fatal blood clot after surgery is higher and lasts for longer than had previously been thought, research led by the University of Oxford has shown.This study published...
Relationship between vitamin D insufficiency in osteoporosis and blood bone biochemistry
Osteoporosis 1,25 (OH) 2 D 3 levels Bone biochemistry
2008/11/25
Background: Vitamin D insufficiency is associated with increased PTH secretion, which in turn leads to bone resorption.
Method : In the present study primary involution osteoporosis and vitamin D 3 l...