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Daily Overfeeding from Protein and/or Carbohydrate Supplementation for Eight Weeks in Conjunction with Resistance Training Does not Improve Body Composition and Muscle Strength or Increase Markers Indicative of Muscle Protein Synthesis and Myogenesis in Resistance-Trained Males
Protein carbohydrate muscle strength hypertrophy muscle protein synthesis myogenesis
2016/3/11
This study determined the effects of heavy resistance training and daily overfeeding with carbohydrate and/or protein on blood and skeletal muscle markers of protein synthesis (MPS), myogenesis, body ...
Combined L-citrulline and glutathione supplementation increases the concentration of markers indicative of nitric oxide synthesis
Nitric oxide L-citrulline L-arginine Glutathione Resistance exercise
2015/7/30
Nitric oxide (NO) is endogenously synthesized from L-arginine and L-citrulline. Due to its effects on nitric oxide synthase (NOS), reduced glutathione (GSH) may protect against the oxidative reduction...
The Relationships Between Simulated Tennis Performance and Biomarkers for Nitric Oxide Synthesis
Blood lactate heart rate nitric oxide stroke performance tennis
2015/5/15
Tennis performance requires a good aerobic endurance and recovering capacity. Nitric oxide (NO) is a gas which is not only a vasodilator and antioxidant but it also regulates the use of oxygen and glu...
The Role of Post-Exercise Nutrient Administration on Muscle Protein Synthesis and Glycogen Synthesis
Protein supplementation carbohydrate supplementation anabolism
2015/5/5
Nutrient administration following an exercise bout vastly affects anabolic processes within the human body, irrespective of exercise mode. Of particular importance are protein and carbohydrates whereb...
Regulation of Muscle Glycogen Repletion, Muscle Protein Synthesis and Repair Following Exercise
Carbohydrate nutrients insulin glucose amino acids
2015/3/13
Recovery from prolonged strenuous exercise requires that depleted fuel stores be replenished, that damaged tissue be repaired and that training adaptations be initiated. Critical to these processes ar...
Synthesis and Mechanistic Studies of a Novel Homoisoflavanone Inhibitor of Endothelial Cell Growth
Endothelial Cell Growth Synthesis and Mechanistic
2014/11/25
Preventing pathological ocular angiogenesis is key to treating retinopathy of prematurity, diabetic retinopathy and age-related macular degeneration. At present there is no small molecule drug on the ...
Dexamethasone Suppresses Histamine Synthesis by Repressing both Transcription and Activity of HDC in Allergic Rats
allergy dexamethasone HDC histamine rats
2010/11/19
In TDI-sensitized rats, nasal allergy-like behaviors such as sneezing and watery rhinorrhea were induced. Histamine content, HDC activity and HDC mRNA expression in nasal mucosa were also significantl...
Induction of IgE synthesis by genetically modified CD8+ T cells of a patient with adenosine deaminase deficiency
CD40 ligand CD8+ T cells gene therapy IgE production interleukin-4
2010/11/26
We have previously reported that an adenosine deaminase (ADA)-deficient patient treated with T cell-directed gene therapy had an increase in serum IgE levels, despite a marked inversion of the CD4/CD8...
Regulatory mechanisms of human IgE synthesis
activation-induced cytidine deaminase adaptor molecule germline Cε transcription IgE isotype switching switch recombination machinery
2010/11/24
The induction of allergen-specific IgE synthesis requires the cognate interactions between B and T helper (Th) 2 cells. The B cell-activating signal for IgE synthesis is delivered through interleukin ...