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Ethical issues around phase I and phase III clinical trials in cancer
cancer Ethical issues
2017/4/10
The results of phase III (randomised) cancer clinical trials underpin evidence-based clinical practice. A standard comparator (control arm) is crucial so that the real value of an intervention can be ...
Management of juxta articular giant cell tumors around the knee by custom mega prosthetic arthroplasty
Custom mega prosthesis juxta articular giant cell tumour outcome
2008/11/25
Background: Juxtaarticular giant cell tumors around the knee are common and pose a special problem of reconstruction after tumor excision. This article analyzes the functional outcome after resection ...
Multicentric giant cell tumor around the knee
Amputation arthrodesis arthroplasty curettage giant cell tumor
2008/11/25
A case of multicentric giant cell tumor with synchronous occurrence in all three bones around the knee is reported here in view of its rarity. A 33-year-old average built male reported with complaints...
Reconstructive procedures for segmental resection of bone in giant cell tumors around the knee
Enbloc resection giant cell tumor reconstruction of knee
2008/11/25
Background: Segmental resection of bone in Giant Cell Tumor (GCT) around the knee, in indicated cases, leaves a gap which requires a complex reconstructive procedure. The present study analyzes variou...
Resection arthrodesis for giant cell tumors around the knee
Giant cell tumor knee resection arthrodesis
2008/11/25
Background: Giant cell tumors (GCTs) of bone are aggressive benign tumors. Wide resection is reserved for a small subset of patients with biologically more aggressive, recurrent and extensive tumors. ...