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Reconstitution of mouse inner ear sensory development from pluripotent stem cells
Inner ear Pluripotent stem cells Hair cells
2015/5/21
The inner ear contains specialized sensory epithelia that detect head movements, gravity and sound. Hearing loss and imbalance are primarily caused by degeneration of the mechanosensitive hair cells i...
Sphingosine 1-phosphate enhances excitability of sensory neurons through sphingosine 1-phosphate receptors 1 and/or 3
sphingosine 1-phosphate S1P excitability sensory neurons G protein-coupled receptors
2015/5/21
Sphingosine 1-phosphate (S1P) is a bioactive sphingolipid that has proven to be an important signaling molecule both as an extracellular primary messenger and as an intracellular second messenger. Ext...
Difficulties Associated with the Study of Action Potential After-potentials in Rat Cultured Sensory Neurones
Ryanodine after-potentials cultured sensory neurones apamin and niflumic acid
2009/6/29
We investigated the properties of action potential after-potentials in cultured dorsal root ganglion neurones from neonatal rats using the whole cell patch clamp technique. The aims of this study were...
Congenital Sensory Neuropathy as a Differential Diagnosis for Phagocytic Immunodeficiency
Congenital defect Hereditary Sensory and Autonomic Neuropathies
2010/2/3
There are few reports about congenital indifference to pain or Hereditary and Sensory Autonomic Neuropathy (HSAN). Several investigations for pathophysiology of this syndrome have been performed and d...
Effect of Epinastine Hydrochloride, a Second-generation Histamine H1-receptor Antagonist, on Sensory Neurons in vitro
epinastine histamine H1 antagonists nerve growth factor substance P
2010/11/22
Background: Epinastine hydrochloride (epinastine) is a second-generation histamine H1-receptor antagonist widely used as an anti-allergic and anti-pruritic. To explore possible new aspects of the anti...