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Geldanamycin, a heat-shock protein 90-binding agent, induces thymocyte apoptosis through destabilization of Lck in presence of 12-O-tetradecanoylphorbol 13-acetate
Geldanamycin heat-shock protein 90-binding agent destabilization of Lck 12-O-tetradecanoylphorbol 13-acetate
2009/3/2
Geldanamycin, a heat-shock protein 90 (Hsp90)-binding agent, modulates various cellular activities. The present study found that, although geldanamycin by itself had no effect on thymocyte viability...
Cutaneous Finding in Anti Thymocyte Globulin Induced Serum Sickness
Anti thymocyte globulin Cutaneous Serum sickness
2010/2/1
Polyclonal anti-thymocyte globulin (ATG) is used as an immunosuppressive agent in the treatment of aplastic anemia (AA). Serum sickness is a recognized side effect of ATG. We observed abnormal skin ma...