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Oxidative Glutathione Conjugation and Its Novel Role in Activation of the Organophosphorus Insecticide Prothiofos
SN2 reaction by computational chemistry desethyl S-oxide of prothiofos oxon oxidative activation of S-alkylphosphorothiolate oxidative glutathione conjugation of S-alkylphosphorothiolate
2009/3/5
The reaction of prothiofos oxon S-oxide (S-oxide) with glutathione (GSH) by computational chemistry formed GS(EtO)P(O)OC6H3Cl2 and PrS(O)(HO)P(O)OC6H3Cl2 (desethyl S-oxide). Both were produced from ...
A novel function of housefly glutathione S-transferase 6B—Its effect on the retention and increase of insecticidal activity of the insecticide prothiofos
housefly glutathione S-transferase GST6A and 6B resistance suppression oxidative glutathione conjugation of prothiofos oxon
2009/3/5
Housefly glutathione S-transferases 1, 3, 4, 6A and 6B were obtained from organophosphorus (OP)-resistant Yachiyo and susceptible Takatsuki strains, respectively. Over 90% homology was found between...