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A Simple Model of Unbounded Evolutionary Versatility as a Largest-Scale Trend in Organismal Evolution
Largest-Scale Trend Organismal Evolution
2015/7/31
The idea that there are any large-scale trends in the evolution of biological organisms is
highly controversial. It is commonly believed, for example, that there is a large-scale trend in
evolution ...
The algebra of the general Markov model on phylogenetic trees and networks
general Markov model phylogenetic trees
2011/1/5
It is known that the Kimura 3ST model of sequence evolution on phylogenetic trees can be extended quite naturally to arbitrary split systems. However, this extension relies heavily on mathematical pec...
Quantitative model for efficient temporal targeting of tumor cells and neovasculature
Quantitative model efficient temporal targeting
2011/1/5
The combination of cytotoxic therapies and anti-angiogenic agents is emerging as a most promising strategy in the treatment of malignant tumors. However, the timing and sequencing of these treatments ...
Bistability and resonance in the periodically stimulated Hodgkin-Huxley model with noise
Bistability Hodgkin-Huxley model
2011/1/6
We describe general characteristics of the Hodgkin-Huxley neuron's response to a periodic train of short current pulses with Gaussian noise. The deterministic neuron is bistable for antiresonant frequ...