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TRANSCRIPTIONAL REGULATION OF THE HUMAN ALCOHOL DEHYDROGENASES AND ALCOHOLISM
exon arrays differential gene expression alternative splicing
2015/5/25
Alcohol dehydrogenase (ADH) genes encode proteins that metabolize ethanol to acetaldehyde. Humans have seven ADH genes in a cluster. The hypothesis of this study was that by controlling the levels of ...
Transcriptional regulation of ATF4 is critical for controlling the Integrated Stress Response during eIF2 phosphorylation
Transcriptional regulation ATF4
2015/5/25
In response to different environmental stresses, phosphorylation of eIF2 (eIF2P) represses global translation coincident with preferential translation of ATF4. ATF4 is a transcriptional activa...
Transcriptional Regulation of Retinal Progenitor Cells Derived from Human Induced Pluripotent Stem Cells.
Stem Cell Human iPS Differentiation Development Retina
2015/5/22
In order to develop effective cures for diseases and decipher disease pathology, the need exists to cultivate a better understanding of human development. Existing studies employ the use of animal mod...