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提供了由哺乳动物YAP蛋白或具有转录控制活性的片段的融合蛋白的与细胞全能性和转录激活结构域相关的基因编码的蛋白、编码核苷酸序列、表达载体及其组合物,以及使用该融合蛋白诱导多能干细胞的方法。
延缓衰老,制备恶性人骨髓间充质干细胞的方法可抗选择性。 制备方法, 第二密码子的253个氨基酸残基的FOXO3蛋白, 丝氨酸密码子编码丙氨酸突变的密码子,FOXO3蛋白密码子的第315位氨基酸残基,丝氨酸密码子编码丙氨酸突变的密码子编码2个突变中的一个突变,编码多能干细胞的基因组包括该步骤。 制备的重组间充质干细胞,并进一步提供其在移植治疗中的用途。 [附图]
In this talk, I will present a proof a decomposition formula of Kazhdan-Lusztig basis for the elements in the lowest two-sided cell of an affine Weyl group. This formula can be used to determine the l...
Researchers at MIT and Harvard University have designed a way to selectively turn on gene therapies in target cells, including human cells. Their technology can detect specific messenger RNA sequences...
The motivic Chern classes of the Schubert cells are the K-theoretic generalizations of the Chern-Schwartz-MacPherson classes in homology. I will report some joint work in progress with L. Mihalcea and...
A typical bacterial genome contains more than 4,000 genes, which encode all of the proteins that the cells need to survive. How do cells know just how much of each protein they need for their everyday...
Building on the CRISPR gene-editing system, MIT researchers have designed a new tool that can snip out faulty genes and replace them with new ones, in a safer and more efficient way.
In a single day, enough sunlight strikes Earth to power the world for an entire year—that is, if we can find a way to capture that energy cheaply and efficiently. While the cost of solar energy has de...
Checkpoint inhibitor drugs have been a gamechanger for many cancer patients. Yet around 70% don’t respond to these medications, which work by removing the “brakes” on the immune system’s response to a...
分子遗传学前沿讲座:RNA structure, a hidden regulator in living cells(时间:2022年7月27日14:00)。
Within a given tissue or organ, cells may appear very similar or even identical. But at the molecular level, these cells can have small differences that lead to wide variations in their functions.
Perovskites hold promise for creating solar panels that could be easily deposited onto most surfaces, including flexible and textured ones. These materials would also be lightweight, cheap to produce,...
Cells in complex organisms undergo frequent changes, and researchers have struggled to monitor these changes and create a comprehensive profile for living cells and tissues. Historically researchers h...
MIT researchers have discovered that before cells start to divide, they do a little cleanup, tossing out molecules that they appear not to need anymore.
Reducing the use of fossil fuels will have unintended consequences for the power-generation industry and beyond. For example, many industrial chemical processes use fossil-fuel byproducts as precursor...

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