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Yale scientists edit gene mutations in inherited form of anemia
Yale scientists edit gene mutations inherited form anemia
2016/11/4
A Yale-led research team used a new gene editing strategy to correct mutations that cause thalassemia, a form of anemia. Their gene editing technique provided corrections to the mutations and alleviat...
Inherited pancreatic cancer
Pancreatic cancer genetic tumor susceptibility syndrome genetic pancreatic cancer
2017/2/22
Up to 10% of pancreatic cancer cases have a heritable component. Some of these are clearly defined tumour predisposition syndromes known as hereditary pancreatic cancers, but most are familial cases, ...
Inherited hemolytic disorders with high occurrence of b-thalassemia in Sindhi community of Jabalpur town in Madhya Pradesh, India
Public health Blood groups Hemoglobin disorders β-thalassemia syndrome G6PD deficiency India
2015/7/15
Hereditary hemolytic disorders such as hemoglobin disorders, β-thalassemia syndrome, G6PD deficiency, and ABO and Rhesus blood groups are the most common public health problems in India. Community gen...
Hypomethylation of the Paternally Inherited LRRTM1 Promoter Linked to Schizophrenia
epigenetics parental imprint sibling pair psychosis
2015/5/5
Epigenetic effects on psychiatric traits remain relatively understudied, and it remains unclear what the sizes of individual epigenetic effects may be, or how they vary between different clinical popu...
Inherited cancer susceptibility syndromes in paediatric practice
Inherited cancer susceptibility syndromes
2015/3/24
Since the development of the “two hit hypothesis” by Alfred Knudson to explain the familial nature of cases of bilateral retinoblastoma,1 there has been growing recognition of the inherited nature of ...
Inherited Thrombophilia and Recurrent Pregnancy Loss
Inherited Pregnancy loss Thrombophilia
2015/10/9
Background:: Recurrent pregnancy loss (RPL) is a common health problem. The polymorphisms G20210A of prothrombin gene (FII G 20210A), and G 1691A of factor V gene (Factor V Leiden, FVL) are the most e...
Inherited structures in deformations of Poisson pencils
Inherited structures deformations of Poisson pencils Mathematical Physics
2011/9/5
Abstract: In this paper with study some properties of bi-Hamiltonian deformations of Poisson pencils of hydrodynamic type. More specifically, we are interested in determining those structures of the f...
On properties not inherited by monoids from their Schutzenberger groups
Complete rewriting systems Finitely presented groups and monoids Finiteness conditions
2011/1/20
We give an example of a monoid with finitely many left and right ideals, all of whose Sch¨utzenberger groups are presentable by finite complete rewriting systems, and so each have finite derivation ty...
Directional transfer of the genic multiple allele inherited male sterile line in Chinese cabbage
Chinese cabbage genetic male sterile line transfer
2010/9/10
A “directional transfer program” was designed and carried out according to the genotype on the male sterility locus of the target line, in order to improve the utilization of the multiple-allele inher...
Inherited metabolic disorders of copper transport —Clinical features and pathophysiology of Wilson disease, Menkes disease and aceruloplasminemia—
Inherited metabolic disorders copper transport —Clinical features Wilson disease Menkes disease
2009/4/1
Copper is an essential trace metal. Proteins exploit the unique redox nature of this metal to undertake a series of facile electron transfer reactions using copper as a cofactor in a select number of ...
Inherited Behaviour in Wilkie Collins's The Legacy of Cain: Victorian Studies and Twenty-First-Century Science Policy
Inherited Behaviour Wilkie Collins Legacy of Cain Victorian Studies Twenty-First-Century Science Policy
2010/11/12
The Legacy of Cain (1888), the last novel Wilkie Collins published before his death, is structured as a case study of the respective influences of nature and nurture. The central question is whether t...
High catalase content of rabbit semen appears to be inherited
High catalase rabbit semen inherited
2008/12/25
Reactive oxygen species, as hydrogen peroxide, can be damaging to sperm. Most species have little protective catalase in their semen, but rabbit semen contains substantial amounts of catalase. The...