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Multiscale analysis of morphology and mechanics in tail tendon from the ZDSD rat model of type 2 diabetes
AFM Tension Nanoscale Ultrastructure Modulus
2014/11/6
Type 2 diabetes (T2D) impacts multiple organ systems including the circulatory, renal, nervous and musculoskeletal systems. In collagen-based tissues, one mechanism that may be responsible for detrime...
Chilean crude extract of Ruta graveolens generates vasodilatation in rat aorta at cellular subtoxic concentrations
Ignacio Jofré Fernández Patricia Navarrete Gómez Jorge Parodi Fernando Romero Mejía Raúl Salvatici Salazar
2013/1/28
In Chile elevated percentage of population have cardiovascular diseases, 70% of this populations is a hypertensive peoples. The Ruta graveolens (Ruta) is a medicinal plant used in different parts of t...
Thymoquinone Suppresses Cellular Proliferation, Inhibits VEGF Production and Obstructs Tumor Progression and Invasion in the Rat Model of DMH-Induced Colon Carcinogenesis
Thymoquinone PCNA-LI VEGF Serum Levels
2013/2/19
A myriad of medicinal effects has been attributed to Thymoquinone (TQ), the major biological-active component of Nigella sativa. TQ has been shown to exhibit potent anti-tumor activities. The present ...
Flavin-Containing Monooxygenase (FMO) Protein Expression and Its Activity in Rat Brain Microvascular Endothelial Cells
Rat Microvascular Endothelial Cells Flavin-Containing Monooxygenase (FMO)
2013/2/19
The aim of this study was to examine whether flavin-containing monooxygenase (FMO) protein was expressed in cultured rat brain microvascular endothelial cells (BMECs), which constitute the blood-brain...
Aged rat heart: Modulation of age-related respiratory defects decreases ischemic-reflow injury
Mitochondria Cytochrome Oxidase Complex III Myocardial Infarction Aging
2013/1/29
Myocardial injury increases in the elderly heart during ischemia and reperfusion. Mitochondria, the key targets and sources of injury during ischemia and reperfusion, sustain ischemic damage to the el...
Overexpression of MyoD Attenuates Denervated Rat Skeletal Muscle Atrophy and Dysfunction
MyoD Denervation Rat Skeletal Muscle Atrophy Dysfunction
2013/1/30
Nerve injury commonly contributes to irreversible functional impairment, reconstruction of the function of muscle is big challenge. In denervated skeletal muscle, therapid expression of MyoD mRNA and ...
Synthesis and Influence of Two Quinoxalinone Derivatives on Anxiety- and Depressive-Like Responses in Wistar Rat
Depression Anxiety Quinoxalinone Derivatives Locomotor Activity Wistar Rats
2013/1/30
Two new quinoxalinone derivatives have been synthesized adopting the HONG method, and investigated for some neuropharmacological effects (anxiety- and depressive-like responses) in rats. The present e...
Parabrachial neuron development: Effects of pre- and neonatal undernutrition in the rat
Parabrachial Neurons Development Brainstem Undernutrition Rats
2013/1/30
Pre-and neonatal fasting in the rat has been used as an experimental model to obtain information on how the newborn gustatory system can be damaged, in- terfering with the basic sensory and hedonic pr...
Rock1 Inhibitor Abrogates Chronic Rejection in Rat Cardiac Model System
Chronic Rejection Transplantation ROCK1 RhoA T Cell
2013/1/31
Background: We have shown previously that the abrogation of acute and chronic rejection of rat cardiac allografts occurs through the down-regulation of RhoA pathway and involves the changes in RhoA ki...
Extracting Global System Dynamics of Corticosteroid Genomic Effects in Rat Liver
Global System Dynamics Corticosteroid Genomic Effects Rat Liver
2009/12/24
Extracting Global System Dynamics of Corticosteroid Genomic Effects in Rat Liver.
Classification of BMI control commands from rat's neural signals using extreme learning machine
BMI control rat's neural signals extreme learning machine
2010/2/25
A recently developed machine learning algorithm referred to as Extreme Learning Machine (ELM) was used to classify machine control commands out of time series of spike trains of ensembles of CA1 hippo...
Immunohistochemical detection of ENaCβ in the terminal Schwann cells associated with the periodontal Ruffini endings of the rat incisor
ENaCβ terminal Schwann cells periodontal Ruffini endings rat incisor
2009/5/8
Epithelial sodium channels (ENaCs) are a subfamily of ion channels within the degenerin/ENaC (DEG/ENaC) superfamily. Previous studies have shown the immunolocalization of ENaC in the neural elements...
Limping Rat Provides Sciatica Insights
Limping Rat Sciatica Insights animal model nerve compression
2009/12/17
A newly developed animal model for the painful nerve condition known as sciatica should help researchers diagnose and treat it, according to Duke University bioengineers and surgeons.Sciatica is not a...
Dietary Supplementation of Vitamin E and α-lipoic Acid Upregulates Cell Growth and Signaling Genes in Rat Myocardium
antioxidants vitamin E α-lipoic acidgene expressionmyocardium
2009/4/20
The efficacy of antioxidant supplementation in the prevention of cardiovascular disease appears equivocal, however the use of more potent antioxidant combinations than those traditionally used may exe...
CORTICAL SPREADING DEPRESSION ELICITED IN RAT BRAIN AFTER EXPOSURE TO MICROWAVE FROM GSM MOBILE PHONE
CORTICAL SPREADING DEPRESSION ELICITED RAT BRAIN AFTER MICROWAVE FROM GSM MOBILE PHONE
2009/4/20
The aim of the present work is to evaluate possibility of microwave emitted by cellular phone that can elicit cortical spreading depression (CSD) in rat brain and studying the characteristics of t...