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Activated factor VII (FVIIa) is a very potent coagulant and may be a key determinant of the outcome of a cardiovascular event. The main determinants of FVIIa are the R353Q polymorphism and dietary ...
The R353Q genotype is a major determinant of factor VII coagulant (FVIIc) activity, which is associated with an increased risk of ischemic heart disease (IHD) and elevated plasma triacylglycerol co...
Background:: Preeclampsia is the most common serious disorder during pregnancy and studies show several immune-related processes in its pathophysiology. The role of cytokines and their expression rema...
Background: Ability of athletes in speed or endurance contests somehow is determined by inherited muscle fiber types. One of the important genes involved in sport genetics is ACTN3 that is located on ...
Background: GST is a family of enzymes that are important in protection of the body against oxidative stress.
Background: Mean magnesium intake in the US population does not differ from that in East Asian populations with traditionally low risks of colorectal cancer and other chronic diseases, but the ratio...
Background:Dihydrofolate reductase (DHFR) converts dihydrofolate (DHF) into tetrahydrofolate (THF) and plays an essential role in cell metabolism and cellular growth. Folic acid from multivitamins nee...
Background:6-Desaturase (FADS2) is the rate-limiting step in the polyunsaturated fatty acid (PUFA) biosynthetic pathway.Objective:The aim was to test whether the common deletion [T/-] in the promoter ...
Background: Both genetic and environmental factors affect the risk of colorectal cancer (CRC). Objective: We aimed to examine the interaction between the D1822V polymorphism of the APC gene and dietar...
The objective of the study was to determine whether the exon 1 variant (G→A) at the SRB-I gene is associated with the lipid response to the content and quality of dietary fat in healthy subjects.
Background: Transferrin is the major iron binding protein in human plasma. In black persons, the transferrin CD phenotype has been associated with alterations in certain markers of iron status.Ob...
Background: A common G-to-A substitution in the promoter area (−75 base pairs) of the apolipoprotein A-I gene (APOA1) has been described. The A allele was shown to be associated w...

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