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The effects of sildenafil ciltrate on the lateral geniculate body of adult Wistar rats (Rattus norvegicus)- A histological study
Sildenafil citrate lateral geniculate body decreased cellular population cellular hypertrophy vacuolations Wistar rats
2015/7/15
The histological effect of oral administration of sildenafil citrate (Viagra), commonly used as an aphrodisiac and for the treatment of erectile dysfunction on one of the visual relay centres namely t...
The differential effects of the indazole-carboxylic acid derivative, tolnidamine, on Sertoli cell protein secretion
Indazole-carboxylic acids tolnidamine antispermatogenic agents Sertoli cell
2009/2/23
The indazole-carboxylic acid derivative tolnidamine (TOL) has marked antispermatogenic activity in rats. Previous morphological and biochemical studies indicate that Sertoli cells are one of the tar...
Leydig cell and extracellular matrix effects on Sertoli cell function：biochemical and morphologic studies
Leydig cell extracellular matrix Sertoli cell function
2009/2/23
The reciprocal influence between Leydig and Sertoli cells prepared from pig testis were studied by coculture of both types of cells in either plastic dishes or dishes coated with basement membrane...
Mast cells in the testis, epididymis and accessory glands of the rat：effects of neonatal steroid treatment
Mast cells rat neonatal steroid treatment
2009/2/23
Mast cells in the testis of control adult rats were found almost exclusively around subcapsular blood vessels. Discrete mast cells were distributed throughout the stroma of the epididymis and sex ...
Kinetics of secretion of luteinizing hormone subunits and free alpha, and effects of gonadotropin releasing hormone
luteinizing hormone subunits gonadotropin releasing hormone
2009/2/23
While GnRH is known to stimulate release of pituitary gonadotropins, its acute effects on the kinetics of secretion of the various hormones and subunits are not well characterized. Pulse-chase exp...
Effects of prolactin on luteinizing hormone-stimulated testosterone secretion in isolated perfused rat testis
prolactin testes luteinizing hormone testosterone secretion
2009/2/23
The direct peripheral effect of prolactin on LH-stimulated testosterone secretion was re-evaluated using the intact, isolated, perfused rat testis. In paired experiments, one testis was infused wi...
Effects of cocaine hydrochloride on reproductive function and sexual behavior of male rats and on the behavior of their offspring
cocaine hydrochloride reproductive function sexual behavior male rats offspring
2009/2/23
Cocaine hydrochloride (30, 15, or 0 mg/kg) was administered daily subcutaneously to male rats for a minimum of 72 days. Animals receiving the 15-mg/kg and 0-mg/kg doses were pair-fed with animals re...
Acute effects and long-term sequelae of 1,3-dinitrobenzene on male reproduction in the rat. II. Quantitative and qualitative histopathology of the testis
1,3-dinitrobenzene male reproduction rat
2009/2/23
This study determined the quantitative and qualitative histopathologic effects of a single oral dose of 1,3-dinitrobenzene (48 mg/kg) on the rat testis from 1 to 175 days postexposure. The testis was ...
Acute effects and long-term sequelae of 1,3-dinitrobenzene on male reproduction in the rat. I. Sperm quality, quantity, and fertilizing ability
long-term sequelae 1,3-dinitrobenzene male reproduction rat
2009/2/23
Groups of eight adult male rats were given a single oral dose of 0 or 48 mg/kg of 1,3-dinitrobenzene and sacrificed at 1, 2, 4, 8, 16, 24, 32, 72, and 175 days posttreatment. The groups killed at 17...
Differential effects of（+）and（-）gossypol enantiomers on mitochondrial function and proliferation of cultured TM4 cells
Gossypol isomer TM4 cells mitochondria
2009/2/23
The in vitro effects of (+) and (-)gossypol enantiomers on the mitochondrial functions of mouse transformed Sertoli, TM4 cells were investigated by monitoring mitochondrial rhodamine 123 accumulat...
Effects of ethanol consumption on the morphology of the rat seminiferous epithelium
ethanol consumption morphology rat seminiferous epithelium
2009/2/23
The effects of ethanol consumption on the morphology of the seminiferous epithelium, with particular emphasis on Sertoli cell ultrastructure, were examined during and following pubertal developmen...
Effects of chronic sulpiride-induced hyperprolactinemia on plasma testosterone and its responses to hCG in normal men
Effects of chronic sulpiride-induced hyperprolactinemia plasma testosterone hCG normal men
2009/2/23
To elucidate the effects of sulpiride-induced (300 mg daily) long-term (64 days) hyperprolactinemia on basal and hCG-stimulated plasma testosterone (T), hCG was given to five normal men five times...
Effects of cyclophosphamide on selected cytosolic and mitochondrial enzymes in the epididymis of the rat
cyclophosphamide selected cytosolic mitochondrial enzymes epididymis rat
2009/2/23
The anticancer and immunosuppressive drug cyclophosphamide is extensively used in clinical practice and is known to alter fertility in man. We showed previously that treatment of male rats with lo...
The effects of unilateral, experimental varicocele are not mediated through the ipsilateral testis
varicocele rat testis
2009/2/23
Unilateral varicocele has been associated with diminished male fertility in humans and with bilateral physiologic and histologic changes in the testis of humans and laboratory animals. In particul...
Reversibility of long-term effects of GnRH agonist administration on testicular histology and sperm production in the nonhuman primate
GnRH agonist LH testosterone testis morphology electron microscopy monkeys
2009/2/23
The present investigation evaluates the long-term effects of GnRH agonist treatment on testicular histology, sperm production and the subsequent recovery of these parameters. Four adult rhesus monke...