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Spontaneous lipid peroxidation and production of hydrogen peroxide and superoxide in human spermatozoa. Superoxide dismutase as major enzyme protectant against oxygen toxicity
Human spermatozoa liquid peroxidation superoxide production hydrogen peroxide production
2009/2/23
Spontaneous lipid peroxidation in washed human spermatozoa was induced by aerobic incubation at 32 C and measured by malonaldehyde production; loss of motility during the incubation was determined s...
Reversibility of long-term effects of GnRH agonist administration on testicular histology and sperm production in the nonhuman primate
GnRH agonist LH testosterone testis morphology electron microscopy monkeys
2009/2/23
The present investigation evaluates the long-term effects of GnRH agonist treatment on testicular histology, sperm production and the subsequent recovery of these parameters. Four adult rhesus monke...
Inhibin production by Sertoli cells during testicular regression in the golden hamster
Inhibin production Sertoli cells testicular regression golden hamster
2009/2/23
The objective of this study was to determine if testicular regression in the hamster results in changes in Sertoli cell function that reflect altered pituitary function. Inhibin-like activity was me...
Increased plasma and pituitary prolactin concentrations in adult male rats with selective elevation of FSH levels may be explained by reduced testosterone and increased estradiol production
Increased plasma pituitary prolactin concentrations adult male rats
2009/2/23
The roles of testosterone and estradiol in regulating prolactin concentrations were studied in acutely castrated adult male rats receiving subcutaneous Silastic implants of the sex steroids. Testost...
Impaired estrogen production by Leydig cells of the naturally retained testis in unilaterally cryptorchid boars and stallions
testis cryptorchid boar stallion estrogens
2009/2/23
Estrogen production in vitro was compared for Leydig cells from cryptorchid and scrotal testes in boars and stallions. Animals with natural and experimental cryptorchidism were used. Purified Leydig...
In vitro production of a TRH-homologous peptide and His-Pro diketopiperazine by human semen
TRH-like peptide His-Pro diketopiperazine peptide biosynthesis in semen
2009/2/23
Fresh human semen, diluted 1:1 v/v with 0.15 M NaCl- 0.05 M phosphate, pH 7.5, undergoes a 3-fold increase in total thyrotropin-releasing hormone (TRH) immunoreactivity on incubation at 4 C for 8 to...
Stimulation of sperm production by human chorionic gonadotropin after prolonged gonadotropin suppression in normal men
sperm production human chorionic gonadotropin prolonged gonadotropin suppression normal men
2009/2/20
The precise hormonal milieu required for quantitatively normal spermatogenesis in man is unclear. The authors previously have shown that both supraphysiologic dosages of human chorionic gonadotropin...
Fetal irradiation increases androgen production by dispersed leydig cells of the rat
seminiferous tubule damage fetal irradiation
2009/2/20
Damage to the seminiferous epithelium of the rat has been shown to decrease the concentration of serum testosterone. In these animals, compared to controls, the structure of the Leydig cells sugge...
Effect of gossypol on testicular testosterone production in vitro
gossypol testicular testosterone production
2009/2/19
Testicular minces were utilized to study the effect of gossypol on testosterone production. Testosterone production was assessed in both control nd gossypol treated groups after 0 to 4 hours incubat...
Catecholamine Stimulation of Androgen Production by Mouse Interstitial Cells in Primary Culture
catecholamines Leydig cells androgens cell culture
2009/2/19
The catecholamines isoproterenol, epinephrine, and norepinephrine stimulated androgen production by mouse interstitial cells in primary culture. The amount of androgen produced in response to maximu...
Quantitative Correlation Between Testicular Stem Cell Survival, Sperm Production, and Fertility in the Mouse After Treatment With Different Cytotoxic Agents
stem cells sperm production fertility radiation Adriamycin
2009/2/19
Treatment of mice with high doses of radiation or certain cytotoxic drugs results in killing of spermatogonial stem cells, a prolonged period of reduced sperm production, and infertility. In this ...
Quantitative Correlation Between Testicular Stem Cell Survival, Sperm Production, and Fertility in the Mouse After Treatment With Different Cytotoxic Agents
stem cells sperm production fertility radiation Adriamycin
2009/2/19
Treatment of mice with high doses of radiation or certain cytotoxic drugs results in killing of spermatogonial stem cells, a prolonged period of reduced sperm production, and infertility. In this ...
Effect of Anesthetics on Testosterone Production in Rats
halothane enflurane ether urethan pentobarbital ketamine gonadotropins blood flow
2009/2/18
Changes in testicular vein and peripheral testosterone concentrations in mature rats were monitored during anesthesia with six different agents. Samples taken 2-3 minutes after initial disturbance o...
Estradiol-induced Inhibition of Testosterone Production by Testicular Interstitial Cells Incubated In Vitro
testosterone interstitial cells estradiol testis steroidogenesis
2009/2/18
Testosterone production by testicular interstitial cells incubated in vitro in the presence of 10-8 to 10-6 M 17-estradiol (E2), 17 -estradiol-3-benzoate (E2B), or benzoic acid (B) was examined. Hig...
Production of endothelin by canine prostatic epithelial cells and its stimulatory effects on their growth
Canine prostate ETB receptors cell growth
2009/2/18
The current study has been designed to explore expressions of endothelin (ET) receptors and ETs in the canine prostate and the effect of ETs on canine prostatic epithelial cells. ET receptors were c...