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Background: Persons with Lynch syndrome (LS) have high lifetime risk of developing colorectal tumors (CRTs) because of a germline mutation in one of their mismatch repair (MMR) genes. An important pro...
Increased permeability of the blood-brain barrier (BBB) is important in neurological disorders. Neuroinflammation is associated with increased BBB breakdown and brain injury. Tumor necrosis factor-alp...
Apurinic endonuclease 1/redox effector factor-1 (Ape1/Ref-1 or Ape1) is an essential protein with two distinct functions. It is a DNA repair enzyme in the base excision repair (BER) pathway and a redu...
Introduction: Paragangliomas are mostly localized in the adrenal medulla and they are usually pheochromocytomas, derived from the neural crest, but otherwise mesenteric paragangliomas are extremely ra...
Neuroendocrine tumors of the larynx comprise a rare group of tumors categorized as typical carcinoid, atypical carcinoid, small-cell neuroendocrine carcinomas, and paragangliomas. Atypical carcinoid t...
Tumor-Epilepsy in Southern Iran     Tumor  Epilepsy  Seizure  Iran       2015/9/18
Tumors are responsible for the primary pathology in 10%–30% of cases undergoing operation for chronic epilepsy.1 Temporal lobe epilepsy is the most frequent epilepsy syndrome in adulthood which is dru...
Mucoepidermoid tumors (METs) of the lung are uncommon tumors which are believed to derive from the excretory ducts of the submucosal bronchial glands of the proximal tracheobronchial tree. METs of th...
Evaluation of Tumor Markers in Asthma Patients     Asthma  AFP  CA 125  CA 15-3  CA 19-9  CEA       2009/6/19
Background: Although tumor markers have been used as biomarkers for monitoring response to therapy and detecting early relapse in malignancies, it is well known that most tumor marker increases are n...
Background: Giant cell tumor (GCT) of the spine is uncommon but most aggressive benign tumor of the spine with unpredictable outcome. We present our observation on six cases of GCT of the spine. We tr...
Background: Curettage and wide resection are accepted methods of treatment of giant cell tumor (GCT) of bone. The success rate with curettage in different reports varies widely. There is a paucity in ...
Giant cell tumor (GCT) of bone is a benign but locally aggressive and destructive lesion generally occurring in skeletally mature individuals. Typically involving the epiphysiometaphyseal region of lo...
Giant cell tumor (GCT) of bone is the most frequently over-diagnosed neoplasm in orthopedic pathology because giant cells are a common component of many neoplastic and nonneoplastic conditions of bone...

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