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Rate-Dependent Effects of Dofetilide on Epicardial Monophasic Action Potentials in Isolated Rabbit Heart with Atrial Pacing
Dofetilide Rate dependency Monophasic action potential duration Interventricular dispersion Langendorff perfusion
2009/6/25
Dofetilide (UK 68,798), a new antiarrhythmic agent, blocks potassium channels selectively and acts primarily by prolonging repolarization duration. The aim of this study was to investigate rate-depend...