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Antitussive Effects of the Leukotriene Receptor Antagonist Montelukast in Patients with Cough Variant Asthma and Atopic Cough
atopic cough cough score cough variant asthma leukotriene receptor antagonist montelukast
2010/11/12
In patients with CVA, 2-week treatment with montelukast, clenbuterol, and montelukast plus clenbuterol all significantly decreased cough scores and treatment with montelukast plus clenbuterol was supe...
Effect of Montelukast Treatment on Serum Paraoxonase Activity in Asthmatic Children
Montelukast asthma paraoxonase
2009/6/17
Montelukast, widely used in the treatment of asthma, is a selective and potent oral cysteinyl leukotriene-1 receptor antagonist. In this study, we investigated the effects of montelukast on oxidative ...
A Double-Blind Non-inferiority Clinical Study of Montelukast, a Cysteinyl Leukotriene Receptor 1 Antagonist, Compared with Pranlukast in Patients with Seasonal Allergic Rhinitis
comparative double blind study cysteinyl leukotriene receptor montelukast pranlukast seasonal allergic rhinitis
2010/11/17
Montelukast 5mg, 10mg once daily and the pranlukast 450mg/day showed significant improvements in the change from the baseline in the composite, daytime and nighttime nasal symptom scores, and the impr...
Therapeutic Effect of Montelukast, a Cysteinyl Leukotriene Receptor 1 Antagonist, on Japanese Patients with Seasonal Allergic Rhinitis
cysteinyl leukotriene receptor dose-response relationship montelukast rhinitis allergic seasonal
2010/11/17
Background: Secretion of nasal discharge was enhanced and airway-resistance in the nasal cavity was augmented, resulting in nasal congestion, when leukotrienes were administered to the nasal mucosa. T...
A Randomized Open-Label Comparative Study of Montelukast versus Theophylline Added to Inhaled Corticosteroid in Asthmatic Children
childhood asthma inhaled corticosteroid montelukast peak expiratory flow sustained-release theophylline
2010/11/19
A significant increase in morning PEF was observed in the add-on montelukast group as compared with the add-on theophylline group at Week 2 (change from baseline of 22.8 L/minvs. 8.7 L/min; p = 0.041 ...
Improved Case of Bronchial Asthma by Re-administration of Pranlukast from Montelukast: Evaluation of Eosinophilic Inflammation in the Peripheral Airway
asthma eosinophil cationic protein (ECP) eotaxin induced sputum Pranlukast
2010/11/22
Following the re-administration of Pranlukast, the clinical symptoms disappeared within a few days and pulmonary function improved within 4 weeks. Eosinophils in the induced sputum almost completely d...
A Study of the Usefulness of Anti-inflammatory Treatment for Mild Intermittent Asthma (Step 1): Budesonide vs. Montelukast
airway hyperresponsiveness airway inflammation anti-inflammatory treatment early intervention exhaled nitric oxide induced sputum mild intermittent asthma
2010/11/19
Anti-inflammatory treatment is necessary even for mild intermittent asthma (step 1). We believe that early intervention with anti-inflammatory drugs is important for the prevention of airway remodelin...