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【分析化学学术报告】Mass Spectrometric detection of membrane-bound proteins and their noncovalent interaction partners（图）
membrane-bound proteins noncovalent
2023/6/20
【分析化学学术报告】Mass Spectrometric detection of membrane-bound proteins and their noncovalent interaction partners
A new method for analyzing protein crystals – developed by Cornell researchers and given a funky two-part name – could open up applications for new drug discovery and other areas of biotechnology and ...
AI system can generate novel proteins that meet structural design targets（图）
AI系统 新型蛋白质 可调蛋白质
2023/6/6
MIT researchers are using artificial intelligence to design new proteins that go beyond those found in nature.
One of the major obstacles that those conducting research on carbohydrates are constantly working to overcome is the limited array of tools available to decipher the role of sugars. As a workaround, m...
One of the hallmarks of Alzheimer’s disease is the presence of neurofibrillary tangles in the brain. These tangles, made of tau proteins, impair neurons’ ability to function normally and can cause the...
Despite its minute size, a single cell contains billions of molecules that bustle around and bind to one another, carrying out vital functions. The human genome encodes about 20,000 proteins, most of ...
Proteins’ Fluorescence A Little Less Mysterious（图）
Proteins Fluorescence Little Less Mysterious
2018/2/1
Rice University scientists have effectively quenched a debate over the mechanism behind a fluorescent biosensor that monitors neurons by sensing changes in voltage.The work led by Rice theoretical che...
Cryo-EM images reveal how key biological machine unfolds problem proteins
Cryo-EM images biological machine proteins
2017/7/21
Hand over hand. That's how new, near-atomic resolution, 3-D snapshots show that a key biological machine unfolds a ribbon of protein through its central channel.The machine is a protein complex called...
Investigating folding stability and dynamics of proteins
folding stability dynamics proteins
2017/7/24
Hydrogels are polymer materials that can absorb a large amount of water, making them flexible like human tissue. They are used in a number of medical applications, including contact lenses, wound dres...
Ancient proteins may offer clues on how to engineer proteins that can withstand the high temperatures required in industrial applications, according to new research published in the Proceedings of the...
New computer model shows how proteins are controlled “at a distance”
New computer model shows proteins controlled at a distance
2017/3/14
Enzymes are large proteins that are involved in virtually every biological process, facilitating a multitude of biochemical reactions in our cells. Because of this, one of the biggest effort...
Scientists from Rice University, Baylor College of Medicine and other institutions are using synthetic biology to capture elusive, short-lived snippets of DNA that healthy cells produce on their way t...
Gatekeeping Proteins to Aberrant RNA:You Shall Not Pass
Gatekeeping Proteins Aberrant RNA Not Pass
2016/11/29
Mistakes happen. This is the case in the process of transporting genetic information in cells. How our cells keep errors in this process in check is the subject of a new paper by researchers at the De...
It gets mighty crowded around your DNA, but don’t worry: According to Rice University researchers, your proteins are nimble enough to find what they need.
Rice theoretical scientists studying the mec...
Negative feedback loops help maintain function of mutated proteins
Negative feedback loops maintain function mutated proteins
2016/7/4
Negative feedback is a universal control mechanism that lets a system’s output throttle its input. If an engine revs up, negative feedback tapers its power source. But if the engine slows down, it re-...