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For the first time, molecules dating to the Stone Age have been revived in the lab.
Genomic analyses reveal the genetic basis of early maturity and identification of loci and candidate genes in upland cotton (Gossypium hirsutum L.)
陆地棉 全基因组 重测序方法 SNP变异图谱
2024/5/17
本研究利用收集的436份国内外变异广泛的陆地棉材料，采用全基因组重测序方法，构建了群体的SNP变异图谱，通过对包含136份早熟棉资源在内的356份陆地棉材料进行深度重测序，并结合公共数据库中的80份陆地棉材料共获得了10,118,884个高质量的SNPs。利用全基因组关联分析（GWAS）鉴定到控制陆地棉早熟性的307个显著遗传位点和重要调控基因。两个早熟遗传热点区域位于 D03和A05&...
Genomic structure and expression of the porcine ACTC1 gene
actin, alpha cardiac muscle 1 mRNA pig transcription profiling RT-qPCR
2018/11/23
A partial cDNA (~1200 bp) of the porcine ACTC1 gene was identified in the subtracted foetal hind limb muscle cDNA library (44 days of gestation; using m. biceps femoris cDNA as the driver). Using spec...
New genomic insights reveal a surprising two-way journey for apple on the Silk Road（图）
New genomic two-way journey apple the Silk Road
2017/9/5
Centuries ago, the ancient networks of the Silk Road facilitated a political and economic openness between the nations of Eurasia. But this network also opened pathways for genetic exchange that shape...
NSF issues $14 million in awards for improved genomic tools
NSF $14 million improved genomic tools
2017/7/24
Ten new awards from the National Science Foundation (NSF) totaling $14 million will enable biologists to develop enhanced genomic tools that can reveal new insights into why organisms are structured t...
NSF awards $44 million for genomic research on range of plants,many economically important
NSF $44 million genomic on range of plants economically important
2016/11/4
To advance the basic science needed to improve agricultural practices, reduce demands on environmental resources, and address climate change challenges, the National Science Foundation (NSF)'s Plant G...
Regulocator: A Novel Method for the Identification of Conserved Elements in Genomic DNA
ReguLocator DNA Conserved Elements
2015/5/26
The process of generating RNA message from a gene is termed "transcription," and is performed by aptly named "transcription factors." These transcription factors can function singly or in conjunction ...
OperomeDB: database of condition specific transcription in prokaryotic genomes and genomic insights of convergent transcription in bacterial genomes
Genomics Gene order Transcriptional interference
2015/5/26
My thesis comprises of two individual projects: 1) we have developed a database for operon prediction using high-throughput sequencing datasets for bacterial genomes. 2) Genomics and mechanistic insig...
Implementation of a Laboratory Information Management System To Manage Genomic Samples
Laboratory Workflow Implementation Configuration
2015/5/26
A Laboratory Information Management Systems (LIMS) is designed to manage laboratory processes and data. It has the ability to extend the core functionality of the LIMS through configuration tools and ...
A Rapid and Cost-effective Procedure for Delineation and Utilization of Genomic Microsatellites for Paralleled Genotyping in Vicia faba
Delineation Paralleled Genotyping
2015/4/1
Although more than 400 microsatellite loci are currently available for Vicia faba L. (faba bean), an important
food and feed grain crop legume, they have not yet been used for comprehensive molecula...
Brassica plants have been bred for centuries and result in produce and products diverse enough to show up in supermarkets all over the world. Brassica napus, more commonly known as rapeseed or canola,...
Genomic basis for coral resilience to climate change
acquired stress tolerance Acropora hyacinthus
2015/12/11
Recent advances in DNA-sequencing technologies now allow for
in-depth characterization of the genomic stress responses of many
organisms beyond model taxa. They are especially appropriate for
organ...
ROLE OF GENOMIC COPY NUMBER VARIATION IN ALZHEIMER'S DISEASE AND MILD COGNITIVE IMPAIRMENT
Copy number variation Alzheimer's disease
2015/5/21
Alzheimer's disease (AD) is the most common form of dementia defined by loss in memory and cognitive abilities severe enough to interfere significantly with daily life activities. Amnestic mild cognit...
基因组学研究中一些常用软件的概述An Introduction of Several Programs Used in Genomic Analysis
基因组学 比对 组装 重复序列 基因
2008/1/16
摘要基因组学是以一个物种的全部遗传信息为研究对象，在整体上研究遗传信息的分子组成、组织结构、表达调控和进化等内在机制的基础性学科。基因组学研究中海量数据的存储、管理和检索，以及对这些数据进行挖掘等过程， 必须借助于生物信息学的方法。 目前，大量成熟的软件广泛地应用在基因组学研究中，它们大都可通过互联网免费访问或索取。本文拟对人类基因组计划中常用的一些软件如序列比对、序列组装、重复序列鉴定和基因预测...
灰树花总DNA的制备及基因组文库的构建A Method for Preparation of Genomic DNA FromGrifola frondosa and Construction of a Genomic Library
灰树花 DNA提取 基因组文库
2008/1/8
摘要
灰树花是一种珍贵的药用真菌，因为多糖含量较高，较难获得高质量的总DNA，本文提出了一种制备高质量灰树花总DNA及构建灰树花基因组文库的方法。该方法制备的灰树花总DNA，经Sau3AI酶切后，用于构建基因组文库，可得到2×105个转化子/50mg，平均插入片段为14kb。本研究为下一步克隆灰树花中的基因以及进行其他分子生物学研究奠定了基础。Abstract： Grifola frondos...